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Abstract

In the early decades of the 20th century, there was a significant increase in the prevalence of oestrogen-related diseases. The incidence of oestrogen-related diseases has been rising in some countries, including the United States, and there are now more than 15,000 cases of oestrogen-related diseases being reported in the United States alone (1). This increase in the incidence of oestrogen-related diseases may be attributed to several factors, including increased urbanization, increasing population growth, and a growing awareness of the importance of oestrogen as a treatment for these diseases. The aim of this study was to determine the prevalence and incidence of oestrogen-related diseases in a large population-based outpatient health service in Kebang University Hospital in the Philippines (2). This study aimed to determine the prevalence and incidence of oestrogen-related diseases in the Kebang University Hospital and to assess the impact of the increasing number of cases and the increase in the number of cases associated with oestrogen-related diseases. The study also aimed to determine the prevalence of oestrogen-related diseases in the Kebang University Hospital and to assess the impact of the increase in the number of cases associated with oestrogen-related diseases. In addition, the results were used to determine the prevalence of oestrogen-related diseases in a community-based outpatient health service in Kebang University Hospital and to assess the impact of the increase in the number of cases associated with oestrogen-related diseases.

Author summary

The aim of this study was to determine the prevalence and incidence of oestrogen-related diseases in a community-based outpatient health service in Kebang University Hospital in the Philippines. This is a large outpatient health service in Kebang University Hospital in the Philippines. The study was conducted by using a population-based prospective cohort study in which we evaluated the prevalence of oestrogen-related diseases in patients with oestrogen-related diseases in the outpatient health service. The study aimed to determine the prevalence and incidence of oestrogen-related diseases in a large population-based outpatient health service in Kebang University Hospital in the Philippines.

Abbreviations:WHO, World Health Organization; Kebang University Hospital, Philippines. Kebang University Hospital. The authors thank all the study participants for their contribution to the study.

Introduction

Oestrogen-related diseases have been increasingly identified as the main cause of gynecologic cancer and cardiovascular disease (CVD) in women []. The increasing incidence of oestrogen-related diseases has caused more women to be diagnosed and treated, especially in the first year of life []. The number of cases of oestrogen-related diseases in the United States increased from 1,000 in 2001 to 3,500 in 2015 []. The incidence of oestrogen-related diseases in the population-based outpatient health service (POHS) has risen due to the increasing number of cases, as the number of patients in the hospital increases, particularly the number of women in the hospital who are being treated for oestrogen-related diseases []. Oestrogen-related diseases are considered to be a major risk factor for cardiovascular diseases, and the increasing incidence of these diseases has been linked to an increased risk of heart disease, stroke, diabetes, and high blood pressure []. As a result, there have been many reports of oestrogen-related diseases occurring in the community-based outpatient health service of Kebang University Hospital (KUHS). The epidemiology of oestrogen-related diseases in KUHS is described in several systematic reviews and meta-analyses []. The study was based on a population-based prospective cohort study in which we evaluated the prevalence of oestrogen-related diseases in the community-based outpatient health service in KUHS. This study aimed to determine the prevalence and incidence of oestrogen-related diseases in the Kebang University Hospital in the Philippines.

To determine the prevalence of oestrogen-related diseases in the community-based outpatient health service in Kebang University Hospital in the Philippines, we aimed to conduct a prospective study to identify the prevalence and incidence of oestrogen-related diseases in the community-based outpatient health service. The study was conducted in KUHS from July 2015 to May 2016.

The study was performed according to the Declaration of Helsinki, and the study protocol was approved by the Institutional Review Board (IRB) of KUHS (IRB number 1557) and informed consent was obtained from all participants. The study protocol was registered with the International Prospective Investigation into Cancer and End cause registries database (EPIDEC).

What is Depo-Provera (Medroxyprogesterone acetate)?

Depo-Provera is a contraceptive injection used for contraception. It works by stopping ovulation in women who do not ovulate. This is a hormonal birth control method. Depo-Provera is the same hormone that causes the menstrual cycle to restart during menopause.

Depo-Provera (Medroxyprogesterone Acetate) and birth control pills

Depo-Provera and birth control pills are used to prevent pregnancy. While Depo-Provera and birth control pills are similar in many ways, they have some differences in their uses and side effects.

How does Depo-Provera (Medroxyprogesterone Acetate) work?

Depo-Provera (Medroxyprogesterone Acetate) works by stopping ovulation in women who do not ovulate.

What are the side effects of Depo-Provera (Medroxyprogesterone Acetate)?

Side effects of Depo-Provera (Medroxyprogesterone Acetate) include:

  • Abdominal pain or discomfort
  • Breast tenderness or enlargement
  • Headache
  • Nausea
  • Weight gain
  • Dizziness
  • Abnormal bleeding or bruising
  • Depression or anxiety
  • Weight loss

If you experience any of these side effects while using Depo-Provera (Medroxyprogesterone Acetate), talk to your doctor.

How should I take Depo-Provera (Medroxyprogesterone Acetate)?

The recommended dose of Depo-Provera (Medroxyprogesterone Acetate) is 150 mg twice daily for 7 days.

You should take Depo-Provera (Medroxyprogesterone Acetate) at the same time each day to maintain steady levels of the hormone in your body. You should take Depo-Provera (Medroxyprogesterone Acetate) until you reach your target dose, at which time the pill may be less effective.

How long does Depo-Provera (Medroxyprogesterone Acetate) take to work?

The effects of Depo-Provera (Medroxyprogesterone Acetate) can last up to 21 days, but it may take longer to see the full benefits of treatment.

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What is Provera?

Provera is an oral contraceptive tablet used to prevent pregnancy. It contains the active ingredient called medroxyprogesterone acetate, which is a form of the hormone progesterone. Provera is available in a wide variety of dosages, including the brand-name Provera. Each tablet is carefully weighed, and the weight is recorded. Provera is taken by mouth, typically once or twice daily. The tablet contains a combination of two hormones, a progestin hormone, and a female sex hormone called luteinizing hormone (LH). It is important to note that Provera should not be used if you have any pre-existing conditions such as high blood pressure, high cholesterol, or if you are breastfeeding.

Provera is also known as the "Provera Pill" because it contains the same active ingredient as the brand-name version, the injectable form, and is available in various dosages. It is important to understand that Provera is not a contraceptive, and it is not a birth control method. Provera is not an option for you if you are experiencing any of the following conditions:

  • Irregular menstrual cycles or periods
  • Anovulatory or recurrent bleeding
  • Laparoscopic surgery to remove the lining of the uterus
  • Anovulation (when the lining of the uterus is removed)
  • Bleeding from the ovary or other part of the body that contains the lining of the uterus
  • Anovulation in any other part of the body
  • Bleeding from a part of the body that has a lining of the uterus

How Does Provera Work?

Provera works by blocking the hormone progesterone from releasing an egg during ovulation. The hormone progesterone, which is a female sex hormone, is released by the ovary, which helps to delay the time when ovulation occurs. By doing this, Provera prevents ovulation, which can lead to the development of a thickening of the cervical mucus. It is important to note that Provera does not prevent pregnancy. The contraceptive pill, which contains the active ingredient medroxyprogesterone acetate, is administered during each cycle of the menstrual cycle. During each menstrual cycle, the medication is given to prepare the lining of the uterus and prevent the ovaries from releasing an egg from the ovary. The lining of the uterus, known as the corpus luteum, is the most important site for progesterone. This lining is located between the bones and the follicles. Provera prevents pregnancy by preventing the release of the hormone from the ovary. This medication can be taken daily, in pill form, or in tablet form. It is important to note that Provera does not prevent pregnancy and it does not prevent egg loss. Provera is available in several forms, including pills, tablets, and injections. However, the most common form of Provera is the "Provera Pill" and it is available in a range of strengths and forms. It is important to follow the directions on the pack to prevent pregnancy. If you are experiencing any of the following conditions, you should use Provera as directed by your healthcare provider.

  • Progesterone is required to be present during an ovulation cycle.

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Depo-Provera Injection is used as a contraceptive to prevent pregnancy. Administered every three months, it contains medroxyprogesterone acetate, a progestin hormone that prevents ovulation, thickens cervical mucus, and thins the uterine lining, reducing the likelihood of fertilization and implantation. This method of birth control is suitable for women seeking long-term contraception without daily pills. Besides pregnancy prevention, it may be prescribed to manage menstrual disorders and reduce endometriosis-related pain. Regular medical monitoring is recommended to manage potential side effects and ensure ongoing suitability.

Depo-Provera Injection by Pfizer is a leading contraceptive option, renowned for its efficacy and safety. Back in the 1990s, while working for a pharmaceutical company, she noticed a slight delay in her period. This unexpected side effect made her switch to Injection every six months, reducing the likelihood of fertilization and pregnancy. Since then, she finds renewed vigour with this relatively new medication.